SoZo® Nutritional Beverage
The Most Powerful Natural Anti-Inflammatory on the Planet!
What Is SoZo?
SoZo® is a polyphenol-rich food supplement beverage that has been scientifically designed to incorporate a full spectrum of the most antioxidant-laden fruit and vegetable whole food powders and extracts available in the world today. SoZo is a hand-picked combination of well-studied freeze dried whole foods, fruit and vegetable concentrates, and effective TargeTested™ patented ingredients.
All raw materials for the SoZo formula are obtained from our partner VDF FutureCeuticals. VDF FutureCeuticals provides a wide spectrum of fruit-, vegetable-, bean-, and grain-based ingredients that are rich in a variety of antioxidants and other phytochemicals. Their product lines focuses on items with scientifically proven benefits. Many of their newest nutraceuticals products are patented, proprietary and unique. VDF FutureCeuticals methods of raw material selection, concentration and drying assure that all products have maximum levels of nutrients and are only the highest quality. Their in-house processing, testing laboratories and state-of-the-art quality control assure that each bottle of SoZo contains the promised product quality.
Each of the individual products that make up the SoZo formula has under gone TargeTesting™ by FutureCeuticals.
The foundation of the SoZo® formulation is CoffeeBerry® which at 15,000 ORAC/gram value is the most powerful fruit ever tested by the USDA. CoffeeBerry® is a patented product owned by FutherCeuticals and can only be obtained from them. SoZo has an exclusive licensing agreement with FutherCeuticals for the use of CoffeeBerry® in the beverage market. You could combine the ORAC values of the Blue Berry, the Acai Berry and the Maqui Berry and the CoffeeBerry® would still be over 10 times more powerful
What Are TargeTest™
TargeTest™ is a method of laboratory testing created by FutherCeuticals to facilitate rational product development. The test examines the effects of dietary supplements on target enzymes and markers in the blood. Research has shown that activity of these markers can have effect on chronic health conditions.
· Past research has linked enzymes in human blood to common health concerns.
· TargeTest™ measures the activity of these enzymes.
· The first step is an ex vivo measurement. This step measures effects of an ingredient on human serum. Finger blood is usually sufficient for this testing.
· If the ex vivo test shows a positive result, testing moves to the second step.
· Second step involves acute in vivo human clinical case studies for two hours after ingestion of food material.
· TargeTest™ is a cost-effective and reliable form of testing that can help differentiate ingredients and finished formulation. TargeTest™ can help eliminate wasted research assets by rapidly identifying product functionality. Screening results confirm bioavailability and efficacy in people.
TargeTests™ Results on SoZo Components
VitaBerry+®
Activates: Phase II Proteins (P2P)
Phase II Activators found in certain edible plants have a significant impact on health by helping to combat the damage of oxidative stress. Oxidative stress can trigger inflammation, a condition that can contribute the development of chronic diseases.
· Exercise, poor diet, muscle stress and environment can induce complex signals in the body that produce oxidative stress.
· Oxidative stress triggers inflammation and pain. Long term inflammation can lead to many chronic diseases, especially as the body ages. Inflammation suppresses Phase II Activators levels.
· Researchers have found that consuming selected fruits and vegetables can boost Phase II Activators in the body.
· Phase II Activators work to counteract the complex signals that create oxidative stress. Traditional pain killers can temporarily block the body's ability to send the signals that trigger inflammation. Phase II Activators more completely and more naturally inhibit this activity.
· Research has shown that Phase II Activators prevent harmful enzymes that cause inflammation.
· Phase II Activation can promote reduced inflammation, improved heart health and protection from certain types of cancers.
VitaGrape® VitaBerry® CoffeeBerry®
Activates: Paraoxonase 1 (PON1)
PON1 is a human blood enzyme associated with maintenance of healthy HDL levels and reduction of oxLDL cholesterol activity. Healthy HDL levels have been associated with decreased risk for the development of cardiovascular diseases. Elevated oxLDL levels have been associated with an increased risk for the development of cardiovascular diseases. PON1 activation could be a potential strategy for heart health management.
· HDL levels decrease and oxLDL levels increase as a result of poor diet, lack of exercise, genetics or irregularities in the body's natural cholesterol transportation process.
· Cardiovascular disease can develop as a result of decreased levels of HDL and an accumulation of oxLDL.
· Published research has reported that activation of PON1 can improve lipid metabolism, an important factor in the onset of cardiovascular disease.
· Studies have shown PON1 activation results in elevated HDL serum levels. It is also known that PON1 activation leads to a reduction in accumulation of lipoperoxides in LDL particles. In other words PON1 inhibits the accumulation of oxLDL.
Food materials that can activate PON1 in humans can help maintain healthy HDL levels and reduce harmful oxLDL activity. PON1 activation in humans can help maintain healthy HDL levels and reduce harmful oxLDL activity. PON1 activation could be useful in the maintenance of a healthy cardiovascular system.
VitaBerry® CoffeeBerry®
Activates: Quinone Reductase (QR)
Quinone Reductase (QR) is an enzyme that fights cellular damage caused by toxic compounds in the body. Cell damage from these compounds increases susceptibility to chronic diseases and other certain types of cancer. QR activity is an important indicator of Phase II Activation. Phase II Activation significantly impacts healthy cells by inhibiting the damage of oxidative stress.
· Toxic compounds called quinones enter the body through food.
· Quinones cause the damage and eventual destruction of cells. This damage increases risk of chronic diseases.
· Researchers have identified over 60 active compounds that induce Phase II Activators. One plant compound, sulforaphane, is especially important in activating QR, a potent Phase II Activator.
QR activation can help protect cells in the body from damage by free radicals. Consuming fruits and vegetables that are rich in QR activators can help maintain healthy levels of QR
· VitaGranate® VitaGrape®
Inhibits: Soluble Epoxide (sEH)
Soluble Epoxide Hydrolase (sEH) is a blood enzyme that is responsible for conversion of acids important in maintaining renal vascular function to harmful acids that are attributed to many inflammatory disorders. sEH inhibition could affect hypertension and inflammation and combat the damage of hypertension on healthy arteries.
· Certain acids in the body called epoxyeicosatrienoic (EET) have anti-hypertensive and anti-inflammatory properties. They are important in maintaining renal vascular function.
· sEH converts EET acids into harmful dihydroxyeicosatrienoic (DHET)
· DHET acids have been attributed to many inflammatory disorders including adult respiratory distress syndrome.
· Research has shown that certain foods affect sEH inhibition. sEH inhibition could be a treatment possibility for inflammation-related health concerns.
sEH inhibition could affect heart health, blood pressure, chronic obstructive pulmonary disease (COPD) and carcinogenesis.
VitaGranate®
Inhibits: Angiotensin Converting Enzyme (AEC)
Angiotensin converting enzymes (ACE) inhibitors are heart medications (or food) that widen or dilate your blood vessels to improve the amount of blood your heart pumps and lower blood pressure. ACE inhibitors also increase blood flow, which helps to decrease the amount of work your heart has to do.
· ACE inhibitors are critical in the treatment of heart failure. They can prevent further wreaking of the heart and prolong your life.
· When given after a heart attack, some ACE inhibitors can prevent some of the damage to the heart and improve the survival rate of heart attack patients.
· Some ACE inhibitors have been found to slow the process that leads to kidney damage in many type 2 diabetics.
· In high risk individuals, ACE inhibitors have been shown to decrease the risk of having a heart attack or stroke.
· Research has shown that certain fruits can act as an ACE inhibitor.
CoffeeBerry® VitaBerry+® VitaGrape®
Inhibits: Elastase
Elastase is an enzyme that destroys a number of proteins, including elastin, an elastic substance that supports the structure of organs and tissue. Elastin is an elastic fiber that together with collagen, determines the properties of connective tissue. High Elastase levels have been associated with disorders such as Ulcerative Colitis (UC) and Chronic Pulmonary Disease (COPD)
· Elastase destroys proteins, including elastin.
· The destruction of elastin leads to tissue damage. Elastin is a fiber that supports the structural framework of tissue.
· Tissue damage caused by Elastase plays a role in skin aging, arterial stiffness as artery walls lose elasticity.
· Food that can inhibit Elastase in the body could be useful in the treatment of Elastase-related health conditions.
· Elastase inhibition has been associated with improved skin elasticity, heart health, flexibility of arterial walls, management of COPD and Ulcerative Colitis.
FruiteX B®
FruiteX B® is a unique mineral carbohydrate molecule found in fruits and vegetables (chemically known as calcium fructoborate), represents a significant breakthrough for individuals concerned about bone and joint health, vitality and healthy aging.
FruiteX B® is the world's only food-form source of borates-mineral carbohydrates containing traces of the element boron. These plant based sugars and sugar-alcohols are considered by scientist to be essential for maintenance of healthy levels of serum calcium, magnesium, vitamin D, DHEA, estrogen and testosterone.
Double- Blind Placebo-Controlled Study
· 79% of participants reported significant increases in joint comfort and flexibility.
· Vitamin D deficient participants showed a 19.6% increase in of serum vitamin D3.
· Vitamin D deficient men exhibited a 29% increase in serum testosterone and a 56% in serum DHEA
· CRPs showed a reduction of 37%
· Perhaps the best testament to the product's appeal, subjects in the FruiteX B® group unanimously requested additional product at the end of the study.
What Is the strength of each of these components?
"SoZo lists the individual ingredients in our Proprietary Blend but not the amounts. All the weights of a specific ingredient in the blend are at levels that equal or exceed the manufactures suggested amount per day for maximum results. I will go further in regards to CoffeeBerry® and say that it does exceed 350mgs per 3oz serving of the highest grade of CoffeeBerry® available."
CoffeeBerry Forte® *
143% increase in Brain Derived Neurotrophic Factor (BDNF)
Clinical Trial
BDNF is a protein active in the brain and central and peripheral nervous system with a critical role in neuron development, maintenance, and repair and in protecting against neuron-degeneration. BDNF is important for a variety of processes, including learning, memory, alertness, mood, controlling body weight, and controlling energy metabolism.
Low levels of BDNF have been associated with numerous deleterious conditions, including obesity, diabetes, metabolic syndrome, depression, cardiovascular diseases, cognitive impairment, and Alzheimer's disease
FruiteX B®+ Resveratrol
59% reduction in C-Reactive Protein (CRP's)
65.5% reduction of pro-BNP
Clinical Trial
The CRP test is a general test to check for inflammation in the body. It is not a specific test. That means it can reveal that you have inflammation somewhere in your body, but cannot pinpoint the exact location. A positive test means you have inflammation in the body. This may be due to a variety of different conditions, including: Cancer, Connective tissue disease, Heart Attack, Infection, Inflammatory bowel disease, Lupus, Pneumococcal pneumonia, Rheumatoid arthritis, Tuberculosis
SoZo® Nutritional Beverage
Nutrition Journal Published Clinical Trial
40% reduction in 8-iso-Prostaglandin F2a ( IL-8)
IL-8 is a potent vasoconstrictor, and is considered a gold standard for measuring oxidative stress in vivo. Studies have shown that serum levels of this biomarker are raised under certain inflammatory conditions such as obesity, arthritic and cardiovascular diseases.
39% reduction in Advanced Oxidation Protein Products (AOPP)
AOPPs are a product of plasma protein oxidation-especially oxidation of albumin. Because of its rapid response to changes, it is thought to be suitable for measuring short-term changes in oxidative stress. Serum levels are increased in subjects with inflammatory conditions such as ulcerative colitis and renal failure. Increased AOPP levels also correlate with cardiovascular disease markers-they may have a causal relationship in the development of atherosclerosis.
9% increase in Nitric Oxide (NO)
Nitric oxide works in the body as a vasodilator, increasing blood flow and lowering blood pressure. Those with atherosclerosis, diabetes, and hypertension have been shown impaired nitric oxide pathways.
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